"Working full-time, have no PEM, fibromyalgia pain eliminated." - Oxaloacetate CFS

Oxaloacetate CFS user Kelley Howsare left the following comments in January 2025 on a Youtube video evaluating a study of Oxaloacetate CFS published by Frontiers in Neurology. We're thrilled to see both Kelly's and her daughter's incredible transformation back to work, health, activity and rewarding lives that are PEM-free with healthy sleep and wake cycles. 

Kelley:
I just want to add a comment based on our experience. I've had ME/CFS for over 30 years & my daughter for over 7 years. OAA has been completely transformative for my daughter and me. We started on 100mg and slowly went up to 500mg. We also found that at the start, we felt more sleepy, but in a healthy way - if that makes sense - we napped when sleepy and found our sleep restorative rather than the old non-restorative sleep. We also found after months of experimenting, that I did better on 500mg/day and she did better on about 700-800mg/day. When we went over these amounts, we got a little edgy or anxious. But we are working full-time, have no PEM, only need to sleep 7 hours a night, have had joint restoration and her fibromyalgia pain was eliminated. If you want a discount, the owner of the Benagene brand offers a wholesale account to drs and patients can access it. The cost of customer acquisition is very high in the supplement niche - so right now that costs them $300/customer as we are a very skeptical group (with good reason of course). If anyone wants more of our story with it, please email me at kelley@kelleyhowsare.com.

Another commenter asks:
Does the symptoms come back if you stop taking it?

Kelley:
We aren't sure. We also take LDN and the autoimmune symptoms do come back if we stop that. I don't notice if I miss a day or two of OAA, but I haven't wanted to go longer to experiment yet. I know that there are some things that seemed to have healed completely - like my knee joints work like they did when I was 20 years old - I doubt they would deteriorate if I stopped. I'm sorry I don't have more info than that.

Craig joins in the comments: 
This has been my experience too, I'm at 500mg and also take LDN.  Even the 100mg Oxylacetate was very helpful really!  I now have normal days, but can still slip a little into tiredness or day after PEM.

**Oxaloacetate CFS is a Medical Food intended for use under medical supervision, for the specific dietary management of ME/CFS.